{"id":3103,"date":"2025-11-10T17:29:25","date_gmt":"2025-11-10T17:29:25","guid":{"rendered":"https:\/\/ppsg.ch\/?page_id=3103"},"modified":"2025-11-10T17:29:45","modified_gmt":"2025-11-10T17:29:45","slug":"hmgcr-gen-chromosom-5q13-3-q14","status":"publish","type":"page","link":"https:\/\/ppsg.ch\/?page_id=3103","title":{"rendered":"HMGCR-Gen Chromosom 5q13.3-q14"},"content":{"rendered":"<p>Das Genprodukt des HMGCR-Gens ist das Enzym HMG-CoA-Reduktase, welches massgeblich an der Synthese von Cholesterin in der Leber beteiligt ist. Von Variationen dieses Gens sind haupts\u00e4chlich Statine betroffen, die als Hemmstoffe des Enzyms zur Senkung des Cholesterinspiegels eingesetzt werden. Durch die Ver\u00e4nderungen im Bauplan des Zielenzyms kann die Wirksamkeit der Statine eingeschr\u00e4nkt sein.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Das Genprodukt des HMGCR-Gens ist das Enzym HMG-CoA-Reduktase, welches massgeblich an der Synthese von Cholesterin in der Leber beteiligt ist. Von Variationen dieses Gens sind haupts\u00e4chlich Statine betroffen, die als Hemmstoffe des Enzyms zur Senkung des Cholesterinspiegels eingesetzt werden. Durch die Ver\u00e4nderungen im Bauplan des Zielenzyms kann die Wirksamkeit der Statine eingeschr\u00e4nkt sein.<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":58,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-3103","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.6 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>HMGCR-Gen Chromosom 5q13.3-q14 -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ppsg.ch\/?page_id=3103\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HMGCR-Gen Chromosom 5q13.3-q14\" \/>\n<meta property=\"og:description\" content=\"Das Genprodukt des HMGCR-Gens ist das Enzym HMG-CoA-Reduktase, welches massgeblich an der Synthese von Cholesterin in der Leber beteiligt ist. Von Variationen dieses Gens sind haupts\u00e4chlich Statine betroffen, die als Hemmstoffe des Enzyms zur Senkung des Cholesterinspiegels eingesetzt werden. Durch die Ver\u00e4nderungen im Bauplan des Zielenzyms kann die Wirksamkeit der Statine eingeschr\u00e4nkt sein.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ppsg.ch\/?page_id=3103\" \/>\n<meta property=\"article:modified_time\" content=\"2025-11-10T17:29:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ppsg.ch\/wp-content\/uploads\/2023\/04\/Fotolia_139857590_M-Kopie-2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1715\" \/>\n\t<meta property=\"og:image:height\" content=\"1108\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data1\" content=\"1\u00a0Minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ppsg.ch\\\/?page_id=3103\",\"url\":\"https:\\\/\\\/ppsg.ch\\\/?page_id=3103\",\"name\":\"HMGCR-Gen Chromosom 5q13.3-q14 -\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ppsg.ch\\\/#website\"},\"datePublished\":\"2025-11-10T17:29:25+00:00\",\"dateModified\":\"2025-11-10T17:29:45+00:00\",\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/ppsg.ch\\\/?page_id=3103\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/ppsg.ch\\\/#website\",\"url\":\"https:\\\/\\\/ppsg.ch\\\/\",\"name\":\"ppsg\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/ppsg.ch\\\/#organization\"},\"alternateName\":\"Psychiatrische Praxis St. Gallen\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/ppsg.ch\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"de\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/ppsg.ch\\\/#organization\",\"name\":\"ppsg\",\"alternateName\":\"Psychiatrische Praxis St. Gallen\",\"url\":\"https:\\\/\\\/ppsg.ch\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\\\/\\\/ppsg.ch\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/ppsg.ch\\\/wp-content\\\/uploads\\\/2023\\\/04\\\/400PngdpiLogo.png\",\"contentUrl\":\"https:\\\/\\\/ppsg.ch\\\/wp-content\\\/uploads\\\/2023\\\/04\\\/400PngdpiLogo.png\",\"width\":2672,\"height\":1617,\"caption\":\"ppsg\"},\"image\":{\"@id\":\"https:\\\/\\\/ppsg.ch\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"HMGCR-Gen Chromosom 5q13.3-q14 -","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ppsg.ch\/?page_id=3103","og_locale":"de_DE","og_type":"article","og_title":"HMGCR-Gen Chromosom 5q13.3-q14","og_description":"Das Genprodukt des HMGCR-Gens ist das Enzym HMG-CoA-Reduktase, welches massgeblich an der Synthese von Cholesterin in der Leber beteiligt ist. 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