{"id":3058,"date":"2025-11-10T16:34:32","date_gmt":"2025-11-10T16:34:32","guid":{"rendered":"https:\/\/ppsg.ch\/?page_id=3058"},"modified":"2025-11-10T16:34:32","modified_gmt":"2025-11-10T16:34:32","slug":"slc19a1-gen-chromosom-21q22-3","status":"publish","type":"page","link":"https:\/\/ppsg.ch\/?page_id=3058","title":{"rendered":"SLC19A1-Gen Chromosom 21q22.3"},"content":{"rendered":"

Der vom SLC19A1-Gen kodierte Folat-Transporter ist f\u00fcr die Regulation der intrazellul\u00e4ren Menge an Fols\u00e4ure verantwortlich. Auch Fols\u00e4ure-Antagonisten wie beispielsweise Methotrexat werden \u00fcber diesen Weg in die Zelle transportiert. Verschiedene Varianten des Gens ver\u00e4ndern die Aktivit\u00e4t des Transporters und k\u00f6nnen hierdurch die Wirksamkeit und Vertr\u00e4glichkeit der dar\u00fcber transportierten Arzneistoffe beeinflussen.<\/p>\n","protected":false},"excerpt":{"rendered":"

Der vom SLC19A1-Gen kodierte Folat-Transporter ist f\u00fcr die Regulation der intrazellul\u00e4ren Menge an Fols\u00e4ure verantwortlich. Auch Fols\u00e4ure-Antagonisten wie beispielsweise Methotrexat werden \u00fcber diesen Weg in die Zelle transportiert. Verschiedene Varianten des Gens ver\u00e4ndern die Aktivit\u00e4t des Transporters und k\u00f6nnen hierdurch die Wirksamkeit und Vertr\u00e4glichkeit der dar\u00fcber transportierten Arzneistoffe beeinflussen.<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":112,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-3058","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nSLC19A1-Gen Chromosom 21q22.3 -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ppsg.ch\/?page_id=3058\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"SLC19A1-Gen Chromosom 21q22.3\" \/>\n<meta property=\"og:description\" content=\"Der vom SLC19A1-Gen kodierte Folat-Transporter ist f\u00fcr die Regulation der intrazellul\u00e4ren Menge an Fols\u00e4ure verantwortlich. 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