{"id":3052,"date":"2025-11-10T16:28:52","date_gmt":"2025-11-10T16:28:52","guid":{"rendered":"https:\/\/ppsg.ch\/?page_id=3052"},"modified":"2025-11-10T16:29:52","modified_gmt":"2025-11-10T16:29:52","slug":"nat2-gen-chromosom-8p22","status":"publish","type":"page","link":"https:\/\/ppsg.ch\/?page_id=3052","title":{"rendered":"NAT2-Gen Chromosom 8p22"},"content":{"rendered":"<p>Die vom NAT2-Gen kodierte N-Acetyltransferase ist ein Enzym, welches Stoffe in der Regel so umwandelt, dass sie f\u00fcr den K\u00f6rper leichter eliminierbar sind. Variationen in diesem Gen lassen sich in drei Ph\u00e4notypen unterteilen, die auf der Aktivit\u00e4t des Enzyms basieren: die langsamen, intermedi\u00e4ren und schnellen Acetylierer. Bei langsamem Acetylieren kann es bei Einnahme mancher Medikamente zu unerw\u00fcnschten Nebenwirkungen kommen, da der Arzneistoff zu langsam abgebaut wird. Schnelle Acetylierung wiederum kann zu Unwirksamkeit aufgrund der beschleunigten Metabolisierung f\u00fchren, sch\u00fctzt aber auch besser vor der toxischen Wirkung bestimmter Xenobiotika.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Die vom NAT2-Gen kodierte N-Acetyltransferase ist ein Enzym, welches Stoffe in der Regel so umwandelt, dass sie f\u00fcr den K\u00f6rper leichter eliminierbar sind. Variationen in diesem Gen lassen sich in drei Ph\u00e4notypen unterteilen, die auf der Aktivit\u00e4t des Enzyms basieren: die langsamen, intermedi\u00e4ren und schnellen Acetylierer. Bei langsamem Acetylieren kann es bei Einnahme mancher Medikamente<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":75,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-3052","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.6 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>NAT2-Gen Chromosom 8p22 -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ppsg.ch\/?page_id=3052\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NAT2-Gen Chromosom 8p22\" \/>\n<meta property=\"og:description\" content=\"Die vom NAT2-Gen kodierte N-Acetyltransferase ist ein Enzym, welches Stoffe in der Regel so umwandelt, dass sie f\u00fcr den K\u00f6rper leichter eliminierbar sind. 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