{"id":3046,"date":"2025-11-10T15:35:44","date_gmt":"2025-11-10T15:35:44","guid":{"rendered":"https:\/\/ppsg.ch\/?page_id=3046"},"modified":"2025-11-10T16:25:34","modified_gmt":"2025-11-10T16:25:34","slug":"g6pd-gen-chromosom-xq28","status":"publish","type":"page","link":"https:\/\/ppsg.ch\/?page_id=3046","title":{"rendered":"G6PD-Gen Chromosom Xq28"},"content":{"rendered":"

Der Glucose-6-phosphat-Dehydrogenase (G6PD) Mangel f\u00fchrt zur rezidivierenden h\u00e4molytischen An\u00e4mie. Der G6PD-Mangel kommt h\u00e4ufig in tropischen und subtropischen L\u00e4ndern vor. Ca. 10 % der m\u00e4nnlichen afroamerikanischen Bev\u00f6lkerung sind betroffen. Die Pr\u00e4valenz des G6PD-Mangels in der Schweiz liegt unter 1 %. Ungef\u00e4hr 20 % der heterozygoten Anlagetr\u00e4ger besitzen eine relative Resistenz gegen\u00fcber dem Erreger der Malaria tropica Plasmodium falciparum. Eine verminderte G6PD Enzymaktivit\u00e4t f\u00fchrt zu einem fehlenden Schutz der Erythrozyten gegen\u00fcber oxidativem Stress. Ein G6PD-Mangel kann unter bestimmten Situationen zur Meth\u00e4moglobin\u00e4mie f\u00fchren. Eine akute h\u00e4molytische An\u00e4mie kann beim G6PD-Mangel durch verschiedene Stoffe und Situationen ausgel\u00f6st werden: Favabohnen, Erbsen, Johannisbeeren, Infektionen, metabolische Azidose, Malariamittel Primaquin und Chloroquin, entz\u00fcndungshemmender Arzneistoff Sulfasalazin, Antibiotika Dapson, Sulfamethoxazol, Cotrimoxazol, Nitrofurantoin, Ciprofloxacin, hochdosierte Acetylsalicyls\u00e4ure, Metamizol, Paracetamol, Ascorbins\u00e4ure in Dosen \u00fcber 1 g, Vitamin-K-Analoga.<\/p>\n","protected":false},"excerpt":{"rendered":"

Der Glucose-6-phosphat-Dehydrogenase (G6PD) Mangel f\u00fchrt zur rezidivierenden h\u00e4molytischen An\u00e4mie. Der G6PD-Mangel kommt h\u00e4ufig in tropischen und subtropischen L\u00e4ndern vor. Ca. 10 % der m\u00e4nnlichen afroamerikanischen Bev\u00f6lkerung sind betroffen. Die Pr\u00e4valenz des G6PD-Mangels in der Schweiz liegt unter 1 %. Ungef\u00e4hr 20 % der heterozygoten Anlagetr\u00e4ger besitzen eine relative Resistenz gegen\u00fcber dem Erreger der Malaria tropica<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":50,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-3046","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nG6PD-Gen Chromosom Xq28 -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ppsg.ch\/?page_id=3046\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"G6PD-Gen Chromosom Xq28\" \/>\n<meta property=\"og:description\" content=\"Der Glucose-6-phosphat-Dehydrogenase (G6PD) Mangel f\u00fchrt zur rezidivierenden h\u00e4molytischen An\u00e4mie. Der G6PD-Mangel kommt h\u00e4ufig in tropischen und subtropischen L\u00e4ndern vor. Ca. 10 % der m\u00e4nnlichen afroamerikanischen Bev\u00f6lkerung sind betroffen. Die Pr\u00e4valenz des G6PD-Mangels in der Schweiz liegt unter 1 %. 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Der G6PD-Mangel kommt h\u00e4ufig in tropischen und subtropischen L\u00e4ndern vor. Ca. 10 % der m\u00e4nnlichen afroamerikanischen Bev\u00f6lkerung sind betroffen. Die Pr\u00e4valenz des G6PD-Mangels in der Schweiz liegt unter 1 %. Ungef\u00e4hr 20 % der heterozygoten Anlagetr\u00e4ger besitzen eine relative Resistenz gegen\u00fcber dem Erreger der Malaria tropica","og_url":"https:\/\/ppsg.ch\/?page_id=3046","article_modified_time":"2025-11-10T16:25:34+00:00","og_image":[{"width":1715,"height":1108,"url":"https:\/\/ppsg.ch\/wp-content\/uploads\/2023\/04\/Fotolia_139857590_M-Kopie-2.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Gesch\u00e4tzte Lesezeit":"1\u00a0Minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/ppsg.ch\/?page_id=3046","url":"https:\/\/ppsg.ch\/?page_id=3046","name":"G6PD-Gen Chromosom Xq28 -","isPartOf":{"@id":"https:\/\/ppsg.ch\/#website"},"datePublished":"2025-11-10T15:35:44+00:00","dateModified":"2025-11-10T16:25:34+00:00","inLanguage":"de","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ppsg.ch\/?page_id=3046"]}]},{"@type":"WebSite","@id":"https:\/\/ppsg.ch\/#website","url":"https:\/\/ppsg.ch\/","name":"ppsg","description":"","publisher":{"@id":"https:\/\/ppsg.ch\/#organization"},"alternateName":"Psychiatrische Praxis St. Gallen","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ppsg.ch\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"de"},{"@type":"Organization","@id":"https:\/\/ppsg.ch\/#organization","name":"ppsg","alternateName":"Psychiatrische Praxis St. Gallen","url":"https:\/\/ppsg.ch\/","logo":{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/ppsg.ch\/#\/schema\/logo\/image\/","url":"https:\/\/ppsg.ch\/wp-content\/uploads\/2023\/04\/400PngdpiLogo.png","contentUrl":"https:\/\/ppsg.ch\/wp-content\/uploads\/2023\/04\/400PngdpiLogo.png","width":2672,"height":1617,"caption":"ppsg"},"image":{"@id":"https:\/\/ppsg.ch\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/ppsg.ch\/index.php?rest_route=\/wp\/v2\/pages\/3046","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ppsg.ch\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ppsg.ch\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ppsg.ch\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ppsg.ch\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3046"}],"version-history":[{"count":1,"href":"https:\/\/ppsg.ch\/index.php?rest_route=\/wp\/v2\/pages\/3046\/revisions"}],"predecessor-version":[{"id":3047,"href":"https:\/\/ppsg.ch\/index.php?rest_route=\/wp\/v2\/pages\/3046\/revisions\/3047"}],"wp:attachment":[{"href":"https:\/\/ppsg.ch\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3046"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}