{"id":2896,"date":"2025-05-11T11:43:16","date_gmt":"2025-05-11T11:43:16","guid":{"rendered":"https:\/\/ppsg.ch\/?page_id=2896"},"modified":"2025-05-12T15:29:13","modified_gmt":"2025-05-12T15:29:13","slug":"behandlung-der-zwangsstoerung-ocd","status":"publish","type":"page","link":"https:\/\/ppsg.ch\/?page_id=2896","title":{"rendered":"Behandlung der Zwangsst\u00f6rung (OCD)"},"content":{"rendered":"<h3><span style=\"color: #467aa7;\">Medikament\u00f6se Behandlung<\/span><\/h3>\n<p>Bei Zwangsst\u00f6rung wird in erster Linie Serotonin Wiederaufnahme hemmende Antidepressiva (S-RI) empfohlen. Serotonin- und Noradrenalin Wiederaufnahme hemmende Antidepressiva (SN-RI), Clomipramin (TZA) und andere Antidepressiva werden erst in zweiter und dritter Linie der Behandlungen der Zwangsst\u00f6rung empfohlen. Die S-RI Escitalopram, Fluoxetin, Fluvoxamin, Paroxetin und Sertralin sind Medikamente der Erstlinie. Zweitlinie Medikamente sind Citalopram, Clomipramin, Mirtazapin, Venlafaxin ER. Es gibt gute Hinweise, dass Clomipramin bei der Behandlung von OCD (Level 2) eine \u00e4hnliche Wirksamkeit hat wie S-RI, aber S-RI sind in der Regel besser vertr\u00e4glich.<\/p>\n<h4><span style=\"color: #467aa7;\"><strong>Medikament\u00f6se Therapie\u00a0der Zwangsst\u00f6rung (Evidenzstufen)<\/strong><\/span><\/h4>\n<table width=\"436\">\n<tbody>\n<tr>\n<td width=\"127\"><strong>Medikament<\/strong><\/td>\n<td width=\"94\"><strong>Evidenzstufe<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"127\"><strong><em>Antidepressiva<\/em><\/strong><\/td>\n<td width=\"94\"><\/td>\n<\/tr>\n<tr>\n<td width=\"127\"><strong>S-RI<\/strong><\/td>\n<td width=\"94\"><\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Escitalopram<\/td>\n<td width=\"94\">1<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Fluoxetin<\/td>\n<td width=\"94\">1<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Fluvoxamin<\/td>\n<td width=\"94\">1<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Paroxetin<\/td>\n<td width=\"94\">1<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Sertralin<\/td>\n<td width=\"94\">1<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Citalopram<\/td>\n<td width=\"94\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">IV Citalopram<\/td>\n<td width=\"94\">3<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Citalopram<\/td>\n<td width=\"94\">3<\/td>\n<\/tr>\n<tr>\n<td width=\"127\"><strong>SN-RI<\/strong><\/td>\n<td width=\"94\"><\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Venlafaxin ER<\/td>\n<td width=\"94\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Duloxetin<\/td>\n<td width=\"94\">4<\/td>\n<\/tr>\n<tr>\n<td width=\"127\"><strong><em>Andere Therapien<\/em><\/strong><\/td>\n<td width=\"94\"><\/td>\n<\/tr>\n<tr>\n<td width=\"127\"><strong>Antipsychotika<\/strong><\/td>\n<td width=\"94\"><\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Aripiprazol<\/td>\n<td width=\"94\">1<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Risperidon<\/td>\n<td width=\"94\">1*<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Olanzapin<\/td>\n<td width=\"94\">1*<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Quetiapin<\/td>\n<td width=\"94\">1*<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Haloperidol<\/td>\n<td width=\"94\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Amisulprid<\/td>\n<td width=\"94\">3<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Ziprasidon<\/td>\n<td width=\"94\">4<\/td>\n<\/tr>\n<tr>\n<td width=\"127\"><strong>Antikonvulsiva<\/strong><\/td>\n<td width=\"94\"><\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Topiramat<\/td>\n<td width=\"94\">1*<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Lamotrigin<\/td>\n<td width=\"94\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Pregabalin<\/td>\n<td width=\"94\">3<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Gabapentin<\/td>\n<td width=\"94\">3 (-ve)<\/td>\n<\/tr>\n<tr>\n<td width=\"127\"><strong>Opiate<\/strong><\/td>\n<td width=\"94\"><\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Tramadol<\/td>\n<td width=\"94\">4<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Naltrexon<\/td>\n<td width=\"94\">3 (-ve)<\/td>\n<\/tr>\n<tr>\n<td width=\"127\">Zusatztherapie Morphin<\/td>\n<td width=\"94\">2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table width=\"457\">\n<tbody>\n<tr>\n<td width=\"243\"><strong>SN-MM<\/strong><\/td>\n<td width=\"206\"><\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Phenelzin<\/td>\n<td width=\"206\">2*<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Tranylcypromin<\/td>\n<td width=\"206\">4<\/td>\n<\/tr>\n<tr>\n<td width=\"243\"><strong>TZA<\/strong><\/td>\n<td width=\"206\"><\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Clomipramin (S-RI)<\/td>\n<td width=\"206\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">IV Clomipramin<\/td>\n<td width=\"206\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Desipramin (N-RI)<\/td>\n<td width=\"206\">2 (-ve)<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Clomipramin<\/td>\n<td width=\"206\">2 (-ve)<\/td>\n<\/tr>\n<tr>\n<td width=\"243\"><strong>Andere Antidepressiva<\/strong><\/td>\n<td width=\"206\"><\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Mirtazapin (SN-RAn)<\/td>\n<td width=\"206\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Bupropion (D-RIRe)<\/td>\n<td width=\"206\">3 (-ve)<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Mirtazapin<\/td>\n<td width=\"206\">3<\/td>\n<\/tr>\n<tr>\n<td width=\"243\"><\/td>\n<td width=\"206\"><\/td>\n<\/tr>\n<tr>\n<td width=\"243\"><strong>Anxiolytika<\/strong><\/td>\n<td width=\"206\"><\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Benzodiazepine<\/td>\n<td width=\"206\"><\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Clonazepam<\/td>\n<td width=\"206\">2 (-ve)<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Clonazepam<\/td>\n<td width=\"206\">2 (-ve)<\/td>\n<\/tr>\n<tr>\n<td width=\"243\"><strong>Andere Behandlungen<\/strong><\/td>\n<td width=\"206\"><\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Clonidin<\/td>\n<td width=\"206\">2 (-ve)<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Pindolol<\/td>\n<td width=\"206\">1*<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Celecoxib<\/td>\n<td width=\"206\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Granisetron<\/td>\n<td width=\"206\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie IV Ketamin<\/td>\n<td width=\"206\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Memantin<\/td>\n<td width=\"206\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Ondansetron<\/td>\n<td width=\"206\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie N-Acetylcystein<\/td>\n<td width=\"206\">2<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Riluzol<\/td>\n<td width=\"206\">3<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Lithium<\/td>\n<td width=\"206\">1 (-ve)<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Buspiron<\/td>\n<td width=\"206\">2 (-ve)<\/td>\n<\/tr>\n<tr>\n<td width=\"243\">Zusatztherapie Minocyclin<\/td>\n<td width=\"206\">4 (-ve)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h4><strong><span style=\"color: #467aa7;\">Empfehlungen f\u00fcr Psychopharmakotherapie\u00a0 der Zwangsst\u00f6rung<\/span><\/strong><\/h4>\n<table>\n<tbody>\n<tr>\n<td width=\"111\"><span style=\"font-family: 'Open Sans'; font-size: 16px;\"><strong>Erste Wahl<\/strong><\/span><\/td>\n<td width=\"503\"><span style=\"font-family: 'Open Sans'; font-size: 16px;\">\u00a0Escitalopram, Fluoxetin, Fluvoxamin, Paroxetin, Sertralin<\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"111\"><span style=\"font-family: 'Open Sans'; font-size: 16px;\"><strong>Zweite Wahl<\/strong><\/span><\/td>\n<td width=\"503\"><span style=\"font-family: 'Open Sans'; font-size: 16px;\">\u00a0Citalopram, Clomipramin, Mirtazapin, Venlafaxin ER<\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"111\"><span style=\"font-family: 'Open Sans'; font-size: 16px;\"><strong>Dritte Wahl<\/strong><\/span><\/td>\n<td width=\"503\"><span style=\"font-family: 'Open Sans'; font-size: 16px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-family: 'Open Sans'; font-size: 16px;\">IV Citalopram, IV Clomipramin, Duloxetin, Phenelzin, Tramadol, Tranylcypromin<\/span><\/p>\n<p>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td width=\"111\"><span style=\"font-family: 'Open Sans'; font-size: 16px;\"><strong>Zusatztherapie<\/strong><\/span><\/p>\n<p>&nbsp;<\/td>\n<td width=\"503\"><span style=\"font-size: 16px; font-family: 'Open Sans';\"><strong>\u00a0<\/strong><span style=\"color: #000000;\"><strong>Erste Wahl:<\/strong><\/span>\u00a0Aripiprazol, Risperidon<\/span><\/p>\n<p><span style=\"font-size: 16px; font-family: 'Open Sans';\"><span style=\"color: #000000;\"><strong>Zweite Wahl:<\/strong>\u00a0<\/span>Memantin, Quetiapin, Topiramat<\/span><\/p>\n<p><span style=\"font-size: 16px; font-family: 'Open Sans';\"><span style=\"color: #000000;\"><strong>Dritte Wahl:<\/strong><\/span>\u00a0Amisulprid, Celecoxib, Citalopram, Granisetron, Haloperidol, IV Ketamin, Mirtazapin, N-Acetylcystein, Olanzapin, Ondansetron, Pindolol, Pregabalin, Riluzol, Ziprasidon<\/span><\/p>\n<p><span style=\"font-size: 16px; font-family: 'Open Sans';\"><span style=\"color: #000000;\"><strong>Nicht empfohlen:<\/strong><\/span>\u00a0Buspiron, Clonazepam, Lithium, Morphin<\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"111\"><span style=\"font-family: 'Open Sans'; font-size: 16px;\"><strong>Nicht empfohlen<\/strong><\/span><\/p>\n<p>&nbsp;<\/td>\n<td width=\"503\">&nbsp;<\/p>\n<p><span style=\"font-family: 'Open Sans'; font-size: 16px;\">Clonazepam, Clonidin, Desipramin<\/span><\/p>\n<p>&nbsp;<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>*Widerspr\u00fcchliche Daten; IV = intraven\u00f6s; SN-MM = Monoamino Oxidase Hemmer; SN-RI = Serotonin\u2013Noradrenalin Wiederaufnahme Hemmer; S-RI = Selektiver Serotonin Wiederaufnahme Hemmer; TZA = Trizyklische Antidepressiva; ER = Extended Release; (-ve) = negativ.<\/p>\n<p>**ER = Extended Release; IV = intraven\u00f6s<\/p>\n<p><span style=\"font-size: 14px; color: #808080;\">Modifiziert nach:\u00a0<a style=\"color: #808080;\" href=\"https:\/\/medfam.umontreal.ca\/wp-content\/uploads\/sites\/16\/Canadian-CPG-Anxiety-2014.pdf\">Martin A Katzman, Pierre Bleau, Pierre Blier, Pratap Chokka, Kevin Kjernisted, Michael Van Ameringen, the Canadian Anxiety Guidelines Initiative Group on behalf of the Anxiety Disorders Association of Canada\/Association Canadienne des troubles anxieux and McGill University. (2014). Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders. BMC Psychiatry. 2014;14 Suppl 1:S1<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Medikament\u00f6se Behandlung Bei Zwangsst\u00f6rung wird in erster Linie Serotonin Wiederaufnahme hemmende Antidepressiva (S-RI) empfohlen. Serotonin- und Noradrenalin Wiederaufnahme hemmende Antidepressiva (SN-RI), Clomipramin (TZA) und andere Antidepressiva werden erst in zweiter und dritter Linie der Behandlungen der Zwangsst\u00f6rung empfohlen. Die S-RI Escitalopram, Fluoxetin, Fluvoxamin, Paroxetin und Sertralin sind Medikamente der Erstlinie. Zweitlinie Medikamente sind Citalopram, Clomipramin,<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-2896","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.6 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Behandlung der Zwangsst\u00f6rung (OCD) - Psychiatrische Praxis St. Gallen \u01c0 PPSG<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ppsg.ch\/?page_id=2896\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Behandlung der Zwangsst\u00f6rung (OCD)\" \/>\n<meta property=\"og:description\" content=\"Medikament\u00f6se Behandlung Bei Zwangsst\u00f6rung wird in erster Linie Serotonin Wiederaufnahme hemmende Antidepressiva (S-RI) empfohlen. 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